What is methylation and why should you care?

The methylation process is more important than you might think.

It can affect everything from fat metabolism to energy production, even contributing to the production of DNA.

So let’s explore what methylation is and why you should care.

What is methylation?⠀

Simply put, methylation is the chemical process of transferring one carbon atom and three hydrogen atoms from one substance to another.

While methylation may seem strange or scientific, you are much more familiar with the process than you might think.

This is happening at a cellular level in your body and, in fact, occurs in every cell and tissue.

The methylation process is extremely important. It changes the way proteins behave, impacting enzymes, hormones and genes.

In most healthy individuals, methylation occurs freely.

When we cannot start the methylation process, it impedes our ability to create a significant number of molecules, including: ⠀.

· Glutathione ⠀⠀

· Coenzyme Q10⠀⠀

· Melatonin ⠀⠀

· Serotonin ⠀⠀

· Nitric Oxide

· Norepinephrine⠀

· Epinephrine ⠀

· L-Carnitine ⠀

· Cysteine

· Taurine ⠀

As it contributes to detoxification, impaired methylation can allow toxins to build up in the body.

As a result, a number of problems can arise.

For example, researchers have established a link between abnormal DNA methylation and autoimmune diseases such as lupus. Disruptions in methylation have also been associated with: ⠀.

· Diabetes ⠀

· Chronic obstructive pulmonary disease (COPD)⠀

· Cancer ⠀

· Muscular dystrophy

· Various hereditary genetic diseases ⠀

· Dementia

· Depression ⠀

· Pregnancy or fertility complications ⠀

In addition to contributing to the disease, methylation impairment can also impair well-being, even in individuals without comorbidities.

Methyl groups control energy production, the response to inflammation, the repair of free radical-damaged cells, and the production of glutathione, a powerful antioxidant.

These factors can make you feel like your energy is depleted and your body is unable to recover as quickly as it should.

To some extent, methylation can be promoted through many of the lifestyle adjustments you would make to support overall health, such as stress reduction, alcohol intake, and toxin exposure.

These toxins overload the liver, which plays an essential role in methylation.

However, in people with MTHFR gene variants or other problems that inhibit methylation, these behaviors alone will not be enough to provide the body with enough 5-MTHF.

Therefore, taking the disability test is a good starting point for most individuals.

If you feel sluggish, sore, or otherwise, you may be suffering from a genetic defect that affects methylation.

The Clinic Offers a Methylation Panel test. 

The Methylation Panel can offer insight in patients with:.

  • Questionable detoxification (patients who take hormone therapy, drink alcohol, or have toxin exposure)
  • Cancer risk
  • Cardiovascular disease (non-coronary atherosclerosis, hypertension, coronary artery disease)
  • Psychiatric and mood disorders (schizophrenia, bipolar disorder, anxiety, depression)
  • Neurologic disorders (Parkinson’s disease, cognitive decline)
  • Chronic fatigue
  • Unexplained Infertility and/or Recurrent Miscarrage 

To learn more about what you can do to find the best version of yourself, get in touch, we can help!

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